Celebs Who Ruined Their Faces With Ozempic In 2025

In 2025, Hollywood saw many celebrities adopting a thinner look, accompanied by a noticeable loss of facial elasticity. Despite the use of Botox and fillers, the rapid weight loss from popular drugs left many stars with a gaunt appearance.

Dr. Samuel Golpanian, a Beverly Hills plastic surgeon, explained that GLP-1 drugs can reduce facial fat and affect skin health by impacting white adipose tissue. Over time, these drugs alter the skin’s structure and its ability to rejuvenate, leading to what has been termed “Ozempic face.”

In November, country singer and rapper Jelly Roll revealed a slimmer face on Instagram, sparking discussions. Despite denying the use of weight loss drugs due to fears of side effects, he humorously mentioned considering a facelift to address the changes in his appearance.

In May, Sharon Osbourne was seen in Los Angeles, prompting comments about her changed appearance. Having started Ozempic in 2022, she admitted to going too far with the drug, affecting her metabolism and appearance. She has since stopped cosmetic procedures.

Kelly Osbourne’s appearance at an event in Birmingham led to comparisons with her mother, Sharon Osbourne. Online users remarked on her altered look, with some mistaking her for her mother.

Christina Aguilera’s appearance has fueled rumors of Ozempic use, though she has not confirmed any use of weight loss drugs. In a 2024 interview, she emphasized her disinterest in public opinions about her appearance.

In May, Rosie O’Donnell’s Instagram post showcasing her new look led to discussions about her altered appearance. Many commented on how much her face had changed.

Scott Disick, featured on “The Kardashians,” was seen using Mounjaro for weight loss. After public reactions to his changing appearance, he consulted a nutritionist to address his health and appearance concerns.